Antonio Giordano, MD, PhD. explains what COVID is and how to contain the infection, pointing also to what will require attention next. Please see this special release at http://online.fliphtml5.com/qlnw/zgau/#p=1
Key Immune System Genes Identified to Explain High COVID Deaths and Spread in Northern Italy Versus Fewer Cases and Deaths in the South
Not long after the Coronavirus disease (Covid-19) outbreak in China, Italy was hard-hit by the infection and rapidly became one of the countries with the highest mortality rate. The disease was first detected on February 20 in Lombardy, a region in the Northern area, and rapidly spread throughout the country. The Southern regions and the … Continue reading Key Immune System Genes Identified to Explain High COVID Deaths and Spread in Northern Italy Versus Fewer Cases and Deaths in the South
Despite Promising Lab Results, Most Precision Medicine Therapies for Mesothelioma Fail in the Clinical Setting
Researchers discuss the case of SRC family kinase inhibitors pointing to new directions to tackle translational challenges Newswise — Malignant mesothelioma (MM) is a lethal cancer mainly caused by exposure to asbestos, for which, unfortunately, no current treatment has proven effective, despite the identification of several promising therapeutic targets over the years. SRC, the first … Continue reading Despite Promising Lab Results, Most Precision Medicine Therapies for Mesothelioma Fail in the Clinical Setting
Mesothelioma
Mesothelioma is a malignant tumor that is caused by inhaled asbestos fibers and forms in the lining of the lungs, abdomen or heart. Symptoms can include shortness of breath and chest pain. The life expectancy for most mesothelioma patients is approximately 12 months after diagnosis. Treatment may improve prognosis and can include surgery, chemotherapy or radiation. What Is Mesothelioma? … Continue reading Mesothelioma
Targeting Receptor EphA2 Reduces Bladder Cancer Tumor Growth and Increases Chemotherapy Effectiveness
An international team of investigators has recently discovered that the receptor tyrosine-kinase EphA2 activated by the growth factor progranulin is a tumorigenic driver of bladder cancer progression. The study, “Progranulin/EphA2 axis: A novel oncogenic mechanism in bladder cancer,” has been recently published in the international-peer-reviewed journal Matrix Biology. The paper describes how EphA2 depletion severely blunted … Continue reading Targeting Receptor EphA2 Reduces Bladder Cancer Tumor Growth and Increases Chemotherapy Effectiveness
‘Genetic Shield’ May Explain Lower COVID Mortality in Southern Italy Compared to North
“A 'genetic shield' may have protected southern Italy from the Sars-CoV-2 tsunami that swept the northern regions,” says Antonio Giordano, M.D., Ph.D., Founder and Director of the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University, and Professor of Pathology at the University of Siena, Italy. “The hypothesis needs to be studied before … Continue reading ‘Genetic Shield’ May Explain Lower COVID Mortality in Southern Italy Compared to North
Genetics May Explain High COVID-19 Mortality in Italy, Inform Global Pandemic Response
Newswise — On March 11th 2020 the World Health Organization declared Coronavirus disease (COVID-19) a pandemic. In a few weeks the infection spread across the globe causing hundreds of thousands of deaths worldwide. Italy was the first European country to be hard-hit by the infection and among the countries with a higher mortality rate. During … Continue reading Genetics May Explain High COVID-19 Mortality in Italy, Inform Global Pandemic Response
Dr. Giordano Featured in Forbes Article on COVID-19 Antibody Tests in Italy and USA
The article in Forbes discusses how the USA can learn from Italy, and their antibody testing during the Italy re-opening phase. There are many companies, international and local, which are racing to win the largest share of the COVID-19 antibody testing market in Italy. WHO warns that antibody tests may not be of great value, … Continue reading Dr. Giordano Featured in Forbes Article on COVID-19 Antibody Tests in Italy and USA
CORONAVIRUS EMERGENCY IN SICILY
A GoFundMe page has been set up to help Sicily during this crisis. Money raised will be used to help local organization in Palermo http://www.anirbas.org which assists the homeless by providing masks, food and other sanitary necessities especially in these times also dealing with Coronavirus emergency which especially affects the homeless and unemployed. Help us … Continue reading CORONAVIRUS EMERGENCY IN SICILY
Coronavirus, Antonio Giordano: “There is no connection with climate change”
The director of the Sbarro Institute in Philadelphia explains what COVID-19 is and how to contain the infection but underlines: "Pollution is a worse threat to our health" n the last few days we have witnessed panic scenes due to the spread of the coronavirus: escapes from the red zone, supermarkets taken by storm to stock … Continue reading Coronavirus, Antonio Giordano: “There is no connection with climate change”
