Link Found Between Bladder Cancer and Collagen Receptor, Revealing Possible Treatment Target

A team of investigators has recently discovered that the collagen receptor DDR1 functionally interacts with the insulin-like growth factor system in regulating bladder cancer. The study entitled “Discoidin Domain Receptor 1 functionally interacts with the IGF-I system in bladder cancer” has been recently accepted in the international-peer-reviewed journal Matrix Biology Plus. This work is an international …

Researchers Find Potential New Target for Mesothelioma Treatment

by Tim Povtak    Research & Clinical Trials       Jan 14, 2020 An international research team has identified a novel molecular target with potential to significantly improve future treatment of malignant pleural mesothelioma. The recent findings could lead to a drug that targets key genetic inhibitors often preventing a patient’s own immune system from suppressing mesothelioma …

Lower Survival in Patients with High BMI and HER2+ Metastatic Breast Cancer Treated with Pertuzumab and Trastuzumab

High BMI correlates to lower survival in patients with HER2+ metastatic breast cancer, even among patients showing initial positive response to new anti-HER2 agents pertuzumab and trastuzumab. An international team of researchers found that high BMI correlates to lower survival in patients with HER2+ metastatic breast cancer, even among patients showing initial positive response to …

Virtual reality during chemotherapy could help improve breast cancer patients’ quality of life

Virtual Reality during chemotherapy has been shown to improve breast cancer patients' quality of life during the most stressful treatments, according to a recent study. Breast cancer is, to date, the most frequent oncological disease worldwide, and has an impact both from a physical and psychological point of view. Receiving a breast cancer diagnosis is …

Campus Exhibit Celebrates Women in Science

The special gallery, Life as a Scientist, was on display during fall semester 2019. A photo gallery celebrating the accomplishments of women in science arrived on campus in fall 2019 and was on display in the Science Education and Research Center and Annenberg Hall. Temple’s College of Engineering, College of Science and Technology, Klein College …

Natural Extract to Counter Nephrotoxicity Induced by Mycotoxin OTA

Today a team of researchers from the Department of Veterinary Medicine and Animal Production of the Federico II University of Naples, in collaboration with the Sbarro Health Research Organization (SHRO), at Temple University in Philadelphia, and the Department of Biotechnology at the University of Siena, Itay, has discovered the effectiveness of a new extract, of …

Turmeric and the Anti-Cancer Properties of Curcumin Discussed in Research Review

Curcumin, a polyphenol extracted from Curcuma longa, also known as turmeric, has gained attention from scientists worldwide for its biological properties as an antioxidant, anti-inflammatory, antimicrobial, and antiviral agent. In addition, curcumin’s anticancer potential has been the most described and still remains under investigation. The most significant outcomes have been collected and discussed in the review …

Researchers Probe Emerging Mesothelioma Treatment Targeting PP2A and CDK

A collaborative study of researchers from Thomas Jefferson University, Sbarro Institute for Cancer Research and Molecular Medicine of Temple University, University of Siena, and from the Spanish Center for the Applied Medical Research (CIMA) of the University of Navarra have discovered a novel targetable axis in mesothelioma patients. The finding has been published on December …

Land of Fires: Evaluation of heavy metal blood-levels in populations exposed to toxic waste in southern Italy

The truth of the Veritas study Toxic environmental agents, to which anyone is involuntarily exposed, represent non-negligible risk for human health and, therefore, environmental contamination has become a theme of primary importance worldwide. In Italy, a dramatic example of this situation is represented by the areas of Caserta and Naples, in the Campania region. Illegal …

Gene Involved in Tumor Blood Vessel Formation and Metastasis Reveals New Regulatory Secrets

Pierluigi Scalia and coworkers at the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University in Philadelphia, and the affiliated Italian research organization ISOPROG, have announced the regulatory map of the human EphB4 gene. In particular, Scalia, along with Dr. Stephen J Williams and professor Antonio Giordano, M.D., Ph.D., founder of the Sbarro …