Special COVID-19 Christopher Magazine

Antonio Giordano, MD, PhD. explains what COVID is and how to contain the infection, pointing also to what will require attention next. Please see this special release at http://online.fliphtml5.com/qlnw/zgau/#p=1  

“Omicron: Be Alarmed, not panic! Here is the new management of the pandemic” – Dr. Antonio Giordano

Scientists are examining a new coexistence with the virus: isolation of only positives and changes to quarantines limited to close positive contacts 'Omicron and how it's managed at present' a viewpoint shared by Dr. Antonio Giordano, Founder & Director of Sbarro Health Research Organization (SHRO) http://www.shro.org The Omicron variant with its high transmissibility rates is …

Cancer Immunotherapy Is Not the Holy Grail: A New Study Casts a Shadow

There is no doubt that the use of recently approved drugs to “boost” the immune response to cancer cells represents a novelty that has enriched the arsenal of ammunition against human cancer Nevertheless, even though some of these drugs (i.e. the class of drugs named Immune-checkpoint-Inhibitors, ICi) have been sometimes hailed as “wonder drugs,” the …

No more doubts: e-cigs are less toxic than traditional cigarettes.

International Replica project network validated the conclusion of the most important studies on e-cigs. It also confirmed the lower toxicity of aerosol produced by electronic cigarettes in comparison to conventional ones. Thousands of studies with different and often inconsistent results have so far been the primary snag to evaluate the toxicity of e-cigarettes. An issue …

Age-Related Differences in Inflammation May Shed Light on the Limit of Immunotherapies

Age-Related Differences in Inflammation May Shed Light on the Limit of Immunotherapies Research Alert Scientists at the Sbarro Institute for Cancer Research and Molecular Medicine, Center of Biotechnology, located at Temple University’s College of Science and Technology, working with collaborators in Italy, have described the age-related differences in inflammatory response to an emerging immunotherapy treatment …

Single-cell sequencing and bioinformatic tools applications discussed in Research Review

Nowadays, single-cell RNA sequencing technologies and related bioinformatics tools are emerging as essential devices for dissecting tumors at single-cell resolution and understanding carcinogenesis and drug response mechanisms, representing a turning point in cancer research. The most significant outcomes have been collected and discussed in the review “Single-cell RNA sequencing and bioinformatics as tools to decipher …

Tumor Blood Vessel Growth May Be Target to Treat Glioblastoma and Other Cancers

Figure 1. TMEM230 promotes aggressive tumor behavior in a human cell line model of GBM. Down regulation of TMEM230 resulted both in fewer tumor cells and less vascularization 3D tissue models Figure 2 TMEM230 promotes vascular mimicry by inducing cancer cells to generate vessel like structures. A novel protein regulator of tumor angiogenesis, TMEM230, was …

SHRO’s Giordano Meets with Appropriations Committee Chair on Capitol Hill

Congresswoman Rosa DeLauro (D-CT), Chair of the House Appropriations Committee meets with Dr. Antonio Giordano in Washington. WASHINGTON, D.C. November 4, 2021 – Professor Antonio Giordano, M.D., Ph.D., Neapolitan Oncologist, Director of the Sbarro Institute for Cancer Research at Temple University and founder of the Sbarro Health Research Organization (SHRO), met today with Congresswoman Rosa DeLauro …

Research Supports More Effective Choices Than Ever for Drug-Free Pain Relief During Labor and Delivery

Researchers coordinated by Professor Antonio Giordano, M.D., Ph.D., Founder and Director of the Sbarro Health Research Organization (SHRO) have highlighted the effectiveness of non-pharmacological analgesic techniques during childbirth in a review recently published in the journal Eukaryotic Gene Expression. “The search for alternative analgesic techniques is a promising and exciting research field,” comments the first author, …

Elucidation of Novel mechanisms regulating the tumor suppressor RBL1/p107 levels in mesothelioma and lung cancer cells

Research Alert The retinoblastoma-like (RBL)1/p107 protein is a member of the retinoblastoma (RB) family including the retinoblastoma (RB)1/p105 protein and RBL2/p130. They are key regulators of the cell cycle and play a central role in modulating cell proliferation.  RB proteins act as tumor suppressors and their dysregulation is associated with tumor initiation. However, the mechanisms …

Fungal and Bacterial Biodeterioration of Outdoor Canvas Paintings: The Case of the Cloisters of Quito, Ecuador

A multidisciplinary work of international range for new studies in the biodeterioration of canvas paintings he journal Critical Review In Eukaryotic Gene Expression has just published an interesting article entitled: “Fungal And Bacterial Biodeterioration Of Outdoor Canvas Paintings: The Case Of The Cloisters Of Quito, Ecuador.” The document is available for all the scientific and academic community …