Untreatable Olive Tree Disease Can Be Contained, But Must Be Better Monitored, says SHRO Researcher

  Xylella fastidiosa, subsp. pauca is a bacterial pathogen currently devastating the olive orchards in Southern Italy (Apulia). Due to the epidemic, local production of olive oil has dropped by 90%, olive mills are shut down, the regional economy is suffering, and an invaluable cultural asset is compromised. Keeping the epidemic under control requires the identification of … Continue reading Untreatable Olive Tree Disease Can Be Contained, But Must Be Better Monitored, says SHRO Researcher

Genetic Profiling and Personalized Training: Study Published in Collaboration between U.S. Researchers and the Medical Staff of the SSC Napoli

A study recently published in the international scientific Journal of Cellular Physiology is the result of a collaboration between the Sbarro Health Research Organization (SHRO), a team of Italian researchers, and the Medical Staff of the SSC Napoli, one of the leading soccer clubs in Italy’s Serie A league. The article, "Genomic analysis reveals association of … Continue reading Genetic Profiling and Personalized Training: Study Published in Collaboration between U.S. Researchers and the Medical Staff of the SSC Napoli

Oncolytic Viruses Against Mesothelioma: A Possible Weapon to Shrink Cancer and Boost the Antitumoral Immune Response

Mesothelioma is a deadly cancer mainly caused by exposure to asbestos or other toxic mineral fibers. Currently, there is no effective cure against this disease and life expectancy of patients with mesothelioma remains very low. Virotherapy, which is based on the use of viruses to fight cancer cells, has long been investigated as a possible … Continue reading Oncolytic Viruses Against Mesothelioma: A Possible Weapon to Shrink Cancer and Boost the Antitumoral Immune Response

Regulation of Cancer Promoting Molecule EphB4 Offers Potential Treatment Target for Mesothelioma, Other Cancers

A novel cancer-promoting molecular mechanism has been discovered by Pierluigi Scalia, M.D., Ph.D., with his co-workers at the Sbarro Institute for Cancer Research and Molecular Medicine, Division of Biology, Temple University, the Department of Medical Biotechnologies at University of Siena, Italy  and the Italian non-profit research organization ISOPROG, in collaboration with the Center of Biocomputational … Continue reading Regulation of Cancer Promoting Molecule EphB4 Offers Potential Treatment Target for Mesothelioma, Other Cancers

New Natural Therapeutic Agent to Fight Diabetic Nephropathy

A team of researchers have published in the Journal of  Cellular Physiology that a new natural extract is able to inhibit the development of diabetic nephropathy, a kidney disease that is increasing in incidence throughout the world. "The new extract of natural origin, obtained from red oranges and lemons, is rich in cyanidin 3-glucoside and other polyphenols,” … Continue reading New Natural Therapeutic Agent to Fight Diabetic Nephropathy

Exploiting RB1 Predictive Value for Cancer Therapy in the Clinical Setting: Lost in Translation

Newswise — The RB1 protein, named after the pediatric tumor retinoblastoma, was discovered in the 80s as the first tumor suppressor and, since then, its pathway has been found inactivated in most human cancers. RB1 ability to halt tumor development and growth has been mainly ascribed to its function in cell cycle regulation, which directly … Continue reading Exploiting RB1 Predictive Value for Cancer Therapy in the Clinical Setting: Lost in Translation

Cervical Cancer During Pregnancy, Though Serious, is Highly Treatable According to New Research Review

Newswise — A team of researchers in the Gynecologic Oncology Unit of the University Hospital of Bologna, in collaboration with Professor Antonio Giordano from the Sbarro Health Research Organization, has published a revision of the literature about cases of cervical cancer in pregnancy, with the addition of new cases treated at the University Hospital of … Continue reading Cervical Cancer During Pregnancy, Though Serious, is Highly Treatable According to New Research Review

Brain Cancer Drug Reactivates Body’s Natural Defenses

Drug reactivates p53 tumor suppressor protein and increases chemotherapy effectiveness in potential glioblastoma breakthrough. Newswise — A team of researchers have published in the International Journal of Oncology that RITA, a drug able to reactivate the oncosuppressor function of p53, could be an effective strategy to treat glioblastoma. The study’s authors include collaborators from the Sbarro Health Research … Continue reading Brain Cancer Drug Reactivates Body’s Natural Defenses

Enzyme Inhibition May Lead to New Melanoma Therapy, Say Researchers at Fox Chase with Support from Sbarro Institute

Newswise — Inhibition of the cellular enzyme thymine DNA glycosylase (TDG) may be an effective treatment for melanoma, according to research published in the journal Oncogene in January. The paper, “Thymine DNA glycosylase as a novel target for melanoma,” describes how inhibition of TDG, known for its role in cell repair and proliferation, may be used to … Continue reading Enzyme Inhibition May Lead to New Melanoma Therapy, Say Researchers at Fox Chase with Support from Sbarro Institute

Decoy Damaged DNA Discovers New Gene Repair Protein

Research identifies HNRNPD as a new safeguard of genome integrity Newswise — Researchers used a synthetic DNA structure to mimic an intermediate of homologous recombination, the most reliable cell cycle process to repair DNA correctly. This DNA structure was then used as bait to capture nuclear proteins in the hopes of identifying a new player … Continue reading Decoy Damaged DNA Discovers New Gene Repair Protein