Old drug could fight brain cancer by starving it to death

Glioblastoma, the most common form of brain cancer is a deadly disease for which at present there is no cure. Now, researchers have published research results that show how repurposing the old drug flavopiridol could be an effective strategy to cut short sugar availability and impair cancer growth.

“The design of new flavopiridol-based formulations, aimed at starving cancer cells cutting short the sugar they’re addicted to, may open up new therapeutic avenues for patients with glioblastoma,” says Antonio Giordano, founder and director of the Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology at Temple University in Philadelphia, PA USA in collaboration with the Department of Medicine, Surgery & Neuroscience at the University of Siena, and University of L’ Aquila Italy.

For more info see:     ScienceDaiy Press Release    or   Pubmed Abstract