A study published in the international journal, Cancer Biology and Therapy, describes research into the correlation between generalized obesity and treatment outcomes in breast cancer patients younger than 45 years old. The study, titled “Body mass index and treatment outcomes following neoadjuvant therapy in women aged 45 years or younger: evidence from a historic cohort,” analyzed body mass index (BMI) in patients treated with chemotherapy (CT) followed by surgery.
“To the best of our knowledge, no previous study has addressed the role of BMI in breast cancer with a focus on young age at diagnosis in women treated with chemotherapy followed by surgery,” says Dr Maddalena Barba, researcher at the Regina Elena National Cancer Institute of Rome and study coordinator. “The modifiable nature of BMI makes its evaluation as a factor associated with treatment outcomes particularly appealing to a research agenda.”
The authors belong to a multidisciplinary Italian-American team led by Prof. Antonio Giordano, Director of the Sbarro Institute for Cancer Research and Molecular Medicine, Temple University of Philadelphia, USA.